Vacancies

Postdoctoral Fellowship in Bioinformatics

Closing Dates Monday 30th November

BREAST-PREDICT

are currently seeking a Postdoctoral Fellow (Level 1 or 2, depending on the level of experience of the candidate) in Bioinformatics in UCD.

Read More Below

Translational Research Co-ordinater

Closing Date Monday 30th November

A Translational Research Co-ordinator

is required to support BREAST-PREDICT research activities, particularly in relation to the clinical study portfolio.

Read More Below

BREAST-PREDICT are currently seeking a Postdoctoral Fellow (Level 1 or 2, depending on the level of experience of the candidate) in Bioinformatics in UCD.

Role:
The successful candidate will carry out the following duties specific to this project:
• Integrate data from the National Breast Cancer Biobank and Database with publically available patient and ‘omics’ data, and prospective clinical trial data.
• Analyse and integrate cancer whole exome sequencing and RNA-seq data to track tumour evolution.
• Carry out computational and statistical analysis aimed at answering research questions pertinent to the goals of the Centre, utilising the resource of the Breast Cancer database.
• Disseminate the results of research through publication in high quality, international, peer-reviewed academic journals and by other appropriate means.
• Support colleagues within BREAST-PREDICT and externally in accessing the database for their research, and in analysing experimental data.
• Attend biannual BREAST-PREDICT team meetings and present your research.
• Attend regular workpackage specific meetings to troubleshoot any issues.
• Prepare grant proposals with a view to developing an independent research career.

Requirements:
• PhD in Bioinformatics, Life Sciences, Computer Science or other relevant discipline, with
research experience in advanced bioinformatics and statistical analysis.
• Proven knowledge in the areas of cancer, computational biology and genomics.
• Relevant experience analysing genomic and transcriptomic data with a focus on prognostic
and predictive gene signatures.
• Proficiency in one or more of the following: R, PERL, Python, Java, C.
• Ability to select and apply the correct statistical methodologies to complex datasets.
• Experience working in a Unix / Linux environment.
• A demonstrated commitment to research and publications.
• An understanding of the operational requirements for a successful research project.
• Evidence of research activity (publications, conference presentations, awards) and future scholarly output (working papers, research proposals), and ability to outline a research project.
• Excellent Communication Skills (Oral, Written , Presentation etc).
• Excellent Organisational and Administrative skills including a proven ability to work to deadlines.

Desirable additional criteria:
• Previous experience of providing Bioinformatics/Biostatistics expertise within a large academic consortium.
• Experience in analysing next generation sequencing data.
• Experience working and utilising bioinformatics pipelines in a high performance computing environment.
• Good working knowledge of Unix, shell/bash and system administration.
• Experience in exploiting existing cancer data sets.
• Experience in setting own research agenda.

Salary: €€33,975 – €46,255 per annum
Appointment on the above range will be dependent on qualifications and experience

For further details visit the UCD Vacancies page at http://www.ucd.ie/hr/jobvacancies/

A Translational Research Co-ordinator is required to support BREAST-PREDICT research activities, particularly in relation to the clinical study portfolio. The position is set at UCD Post-doctoral Research Fellow Level 1 or 2, depending on the level of experience of the candidate.

Role:
The successful candidate will carry out the following duties specific to this project:
• Visit hospital sites around the country, interact with clinical collaborators, and gather data on
available patient samples for BREAST-PREDICT studies.
• Assess what consent is in place for such samples.
• Consult with pathologists on quality control of available tissue blocks.
• Construct Tissue Microarrays (TMAs) from available tumour samples, on-site where
necessary.
• Provide additional support for TMA resources, including staining and manual and digital
scoring analysis.
• Perform extraction of nucleic acids (DNA/RNA) from individual samples for downstream
molecular studies.
• Attend regular workpackage specific meetings to troubleshoot any issues with sample
collection and TMA construction
• Attend biannual BREAST-PREDICT team meetings and present your research.

Requirements:
• PhD in Cancer Biology with specific experience in immunohistochemistry/TMA analysis,
molecular biology techniques and statistics.
• A minimum of 2/3 years postdoctoral research experience.
• Expertise in TMA staining and both manual pathology analysis and and digital image analysis
using Aperio or other software.
• Knowledge in the area of breast cancer research.
• A record of research in Cancer Biology, as evidenced by past and recent publications in high
ranking journals.
• Demonstrated understanding of operational requirements for a successful research project
and managing resources.
• Knowledge and application of the principles underpinning successful grant application.
• Ability to identify and fulfil the academic writing requirements for target publications.
• Proven record of working with team members and PhD students to help build their research
skill and knowledge and to support and guide their professional development.
• Generates new ideas and links and builds upon existing ideas to generate unique concepts
and solutions.

Desirable additional criteria:
• Experience in next-generation sequencing technologies would be advantageous
• Excellent interpersonal skills and the ability to confidently interact with colleagues from both
clinical and academic backgrounds.
• Demonstrated understanding of the value of clinical, academic and commercial information
e.g. Non-disclosure agreements, patient consent forms
• Knowledge of IP processes and knows how to protect findings.

Salary: €38,155 – €42,394 per annum
Appointment on the above range will be dependent on qualifications and experience

For further details visit the UCD Vacancies page at http://www.ucd.ie/hr/jobvacancies/